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14/12/2009 21:45:16
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03/03/2010 22:46:35
Ventilator troubles, Pancakes and Teletubbies!
Sophie has enjoyed making pancakes and of course the Teletubbies!
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A Sleepy Week...
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MITOCHONDRIAL RSS NEWS FEEDS

MedWorm: Mitochondrial Disease

4. The electrophysiological features of HIV peripheral neuropathy
Mitochondrial D-loop variations in paediatric acute myeloid leukaemia: a potential prognostic marker
A case of canine ocular onchocercosis in Portugal
Caspase-3/-8/-9, Bax and Bcl-2 expression in the cerebellum, lymph nodes and leukocytes of dogs naturally infected with canine distemper virus.
SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1 [Enzymology]
Environmental toxins and Parkinson's disease: Putative roles of impaired electron transport chain and oxidative stress
Morphological findings of extraocular myopathy with chronic progressive external ophthalmoplegia.
LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex that Regulates Posttranscriptional Gene Expression in Mitochondria.
Lights on for aminopeptidases in cystic kidney disease
Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy
A general introduction to the biochemistry of mitochondrial fatty acid ?-oxidation
Spinal cord repair in MS: Does mitochondrial metabolism play a role?
Mitochondrial metabolism modulation: a new therapeutic approach for Parkinson's disease.
TRPC Channels and their Implication in Neurological Diseases.
Analysis of differential DNA damage in the mitochondrial genome employing a semi-long run real-time PCR approach
High-Throughput Assay to Measure Oxygen Consumption in Digitonin-Permeabilized Cells of Patients with Mitochondrial Disorders [Endocrinology and Metabolism]
Akt and c-Myc Differentially Activate Cellular Metabolic Programs and Prime Cells to Bioenergetic Inhibition [Molecular Bases Of Disease]
The Transgenic Overexpression of {alpha}-Synuclein and Not Its Related Pathology Associates with Complex I Inhibition [Neurobiology]
A Diagnostic Algorithm for Metabolic Myopathies
Amiodarone-induced liver cirrhosis and parkinsonism: a case report.
A novel HAX1 gene mutation in severe congenital neutropenia (SCN) associated with neurological manifestations
AMPK Activators as Novel Therapeutics for Type 2 Diabetes.
Molecular identification of ancient and modern mammalian magnesium transporters
Involvement of anion exchanger-2 in apoptosis of endothelial cells induced by high glucose through an mPTP-ROS-Caspase-3 dependent pathway
Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer?s and Parkinson?s diseases
Kostmann disease with developmental delay in three patients
Cardiac involvement is frequent in patients with the m.8344A>G mutation of mitochondrial DNA
Expression profiling of mouse embryonic fibroblasts with a deletion in the helicase domain of the Werner Syndrome gene homologue treated with hydrogen peroxide
Epileptic phenotypes in children with respiratory chain disorders
Insights into lysosomal cobalamin trafficking: lessons learned from cblF disease
Mode of action of Nifurtimox and N-oxide-containing heterocycles against Trypanosoma cruzi: is oxidative stress involved?
Aminoglycoside-induced deafness during treatment of acute leukaemia
Lineage-specific positive selection at the merozoite surface protein 1 (msp1) locus of Plasmodium vivax and related simian malaria parasites
Metabolic correlations of glucocorticoids and polyamines in inflammation and apoptosis.
Oxidative Stress, Mitochondrial Bioenergetics and Cardiolipin in Aging.
Dichloroacetate (DCA) enhances tumor cell death in combination with oncolytic adenovirus armed with MDA-7/IL-24.
A role for p53 in mitochondrial stress response control of longevity in C. elegans.
Eponym
Psychopharmacological Neuroprotection in Neurodegenerative Disease: Assessing the Preclinical Data [SPECIAL ARTICLES]
Value of Brain Magnetic Resonance Imaging in Mitochondrial Respiratory Chain Disorders
The first case of mitochondrial acetoacetyl-CoA thiolase deficiency identified by expanded newborn metabolic screening in Italy: the importance of an integrated diagnostic approach
Abnormal growth in mitochondrial disease
Life-long protection from global cerebral ischemia and reperfusion in long-lived Mclk1(+/-) mutants.
The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart [Research Articles]
The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes.
Autophagy during cardiac stress: joys and frustrations of autophagy.
The cardiac mitochondrion: nexus of stress.
Amyloid-beta-Derived Diffusible Ligands Cause Impaired Axonal Transport of Mitochondria in Neurons.
Dissecting Toxicity of Tau and beta-Amyloid.
Biochemical abnormalities in a patient with thymidine phosphorylase deficiency with fatal outcome
Disease mechanisms and protein structures in fatty acid oxidation defects
Molecular Poltergeists: Mitochondrial DNA Copies (numts) in Sequenced Nuclear Genomes
Mechanisms of disease and clinical features of mutations of the gene for mitofusin 2: an important cause of hereditary peripheral neuropathy with striking clinical variability in children and adults
Mitochondrial diseases in childhood: a clinical approach to investigation and management
Analysis of the Liver Mitochondrial Proteome in Response to Ethanol and S-Adenosylmethionine Treatments: Novel Molecular Targets of Disease and Hepatoprotection.
Suppression of ROS generation by 4,4'-diaminodiphenylsulfone in non-phagocytic human diploid fibroblasts.
Clinical features of mitochondrial DNA m.3243A>G mutation in 47 Chinese families
Parkinson's disease: Mitochondrial damage control
OPA1 increases the risk of normal but not high tension glaucoma
Randomised trial of latrepirdine in Huntington Disease
Genomic diversity of sweet potato geminiviruses in a Brazilian germplasm bank.
Severe epilepsy as the major symptom of new mutations in the mitochondrial tRNAPhe gene
A Novel POLG Gene Mutation in 4 Children With Alpers-like Hepatocerebral Syndromes [Observation]
Inherited Metabolic Disorders and Stroke Part 2: Homocystinuria, Organic Acidurias, and Urea Cycle Disorders [Neurological Review]
Hexokinase II gene transfer protects against neurodegeneration in the rotenone and MPTP mouse models of Parkinson's disease
Protective effects of diosgenin in the hyperlipidemic rat model and in human vascular endothelial cells against hydrogen peroxide-induced apoptosis.
Apoptosis and apoptotic mimicry: the Leishmania connection.
Theophylline treatment improves mitochondrial function after upper cervical spinal cord hemisection.
An overview of a cohort of South African patients with mitochondrial disorders
High resolution melting analysis facilitates mutation screening of ETFDH gene: Applications in riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.
Proteomic profiling of non-obese type 2 diabetic skeletal muscle.
Diffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell death
Transforming growth factor [beta]1 mediates apoptotic activity of angiotensin II type I receptor blocker on prostate epithelium in vitro
Mitochondrial dynamics, cell death and the pathogenesis of Parkinson?s disease
Involvement of VDAC1 and Bcl-2 family of proteins in VacA-induced cytochrome c release and apoptosis of gastric epithelial carcinoma cells
Proteome profile in Myotonic Dystrophy type 2 myotubes reveals dysfunction in protein processing and mitochondrial pathways.
Antioxidant defence systems and generation of reactive oxygen species in osteosarcoma cells with defective mitochondria; effect of selenium.
Herbal medicines affect heart drugs
Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration
Endogenous DOPA and dopaquinone modifications on protein tyrosine: Links to mitochondrially-derived oxidative stress via hydroxyl radical.
Mitochondria get a Parkin' ticket
Effect of mitochondrial toxins on evoked somatosensory activity in rats
Induction of parkinsonism-related proteins in the spinal motor neurons of transgenic mouse carrying a mutant SOD1 gene
l-beta-ODAP alters mitochondrial Ca(2+) handling as an early event in excitotoxicity.
A genetic approach to stratification of risk for age-related macular degeneration.
Impact of normothermic perfusion and protein supplementation on human endothelial cell function during organ preservation.
Potential Future Neuroprotective Therapies for Neurodegenerative Disorders and Stroke
The Dietary Flavonoid Quercetin Increases VO2max and Endurance Capacity.
Nitrogen Compounds Prevent H9c2 Myoblast Oxidative Stress-Induced Mitochondrial Dysfunction and Cell Death.
Mitochondrial DNA copy number in peripheral blood is associated with cognitive function in apparently healthy elderly women.
Cyclophilin D-dependent mitochondrial permeability transition is not involved in neurodegeneration in mnd2 mutant mice.
A high throughput electrochemiluminescence assay for the quantification of frataxin protein levels.
Med Sci Monit 2010; 16(2):BR61-67 "Melatonin MT1 and MT2 receptor expression in Parkinson?s disease"
Selected Update: Neurodegenerative disease: Synergistic destruction
The Mitochondrial Pathway of Anesthetic Isoflurane-induced Apoptosis [Molecular Basis Of Cell and Developmental Biology]
Proproliferative Functions of Drosophila Small Mitochondrial Heat Shock Protein 22 in Human Cells [Molecular Basis Of Cell and Developmental Biology]
Antimitochondrial Autoantibodies in Pemphigus Vulgaris: A MISSING LINK IN DISEASE PATHOPHYSIOLOGY [Mechanisms Of Signal Transduction]
A Reaction-Diffusion Model of ROS-Induced ROS Release in a Mitochondrial Network
Animal models of mitochondrial DNA transactions in disease and ageing.
A Reaction-Diffusion Model of ROS-Induced ROS Release in a Mitochondrial Network
Mitochondrial haplogroup H correlates with ATP levels and age at onset in Huntington disease
Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implication in the pathogenesis of the disease
A mitochondria-localized glutamic acid-rich protein (MGARP/OSAP) is highly expressed in retina that exhibits a large area of intrinsic disorder.
Mitochondrial dysfunction and mitophagy activation in blood mononuclear cells of fibromyalgia patients: implication in the pathogenesis of the disease
Mouse models for nuclear DNA-encoded mitochondrial complex I deficiency
Impact of Normothermic Perfusion and Protein Supplementation on Human Endothelial Cell Function During Organ Preservation [ORIGINAL ARTICLES: ADULT CARDIAC]
Cancer as a metabolic disease
Calcium dysregulation in amyotrophic lateral sclerosis.
Triclosan inhibition of mycobacterial InhA in Saccharomyces cerevisiae: yeast mitochondria as a novel platform for in vivo antimycolate assays
A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells [Medical_Sciences]
Abnormal Mitochondrial Dynamics?A Novel Therapeutic Target for Alzheimer's Disease?
AMPK and SIRT1: A Longstanding Partnership?
The protective effect of trihexyphenidyl on the beta-amyloid peptide 25?35-induced cytotoxicity in PC12 cells
An integrated pipeline for next-generation sequencing and annotation of mitochondrial genomes
Nebivolol Attenuates Maladaptive Proximal Tubule Remodeling in Transgenic Rats.
Oxidative stress and plasma aminopeptidase activity in Huntington?s disease
The amyloid precursor protein intracellular domain (AICD) disrupts actin dynamics and mitochondrial bioenergetics
DJ-1-deficient mice show less TH-positive neurons in the ventral tegmental area and exhibit non-motoric behavioural impairments
Transcriptional profile of Parkinson blood mononuclear cells with LRRK2 mutation.
S-Allyl-L-Cysteine Sulfoxide Inhibits Tumor Necrosis Factor-Alpha Induced Monocyte Adhesion and Intercellular Cell Adhesion Molecule-1 Expression in Human Umbilical Vein Endothelial Cells.
Mitochondria-Produced Superoxide Mediates Angiotensin II-Induced Inhibition of Neuronal Potassium Current.
Mitochondrial Energetics and Therapeutics.
Accurate prediction of repeat prostate biopsy outcomes by a mitochondrial DNA deletion assay
Genetic bases of mitochondrial respiratory chain disorders.
Structure-function relationships in feedback regulation of energy fluxes in vivo in health and disease: Mitochondrial interactosome.
Prevalence and natural history of heart disease in adults with primary mitochondrial respiratory chain disease
Mitochondrial DNA Damage Induced by 7-Ketocholesterol in Human Retinal Pigment Epithelial Cells In Vitro [Retinal Cell Biology]
Genetic Risk Factor for Parkinson's Disease
Genetic Risk Factor Identified For Parkinson's Disease: Gene Variant Influences Vitamin B6 Metabolism
Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Abeta peptide.Implications for the pathogenesis of Alzheimer's disease
L-carnitine attenuates oxidant injury in HK-2 cells via ROS-mitochondria pathway.
Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species.
The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-α toxicity involves membrane melatonin receptors
The molecular mechanism of mitochondria autophagy in yeast
Genetic Risk Factor Identified for Parkinson's Disease
Aberrant synthesis of ATP synthase resulting from a novel deletion in mitochondrial DNA in an African patient with progressive external ophthalmoplegia
Genetic risk factor identified for Parkinson's disease
Altered Gene Expression and DNA Damage in Peripheral Blood Cells from Friedreich's Ataxia Patients: Cellular Model of Pathology
Association of endothelial nitric oxide synthase and mitochondrial dysfunction in the hippocampus of scrapie-infected mice
Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium.
Mitochondrial biotransformation of omega-(phenoxy)alkanoic acids, 3-(phenoxy)acrylic acids, and omega-(1-methyl-1H-imidazol-2-ylthio)alkanoic acids: A prodrug strategy for targeting cytoprotective antioxidants to mitochondria.
A non-enzymatic function of 17[beta]-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival
Review: Inherited metabolic disorders and stroke - Part 1
Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.
Inherited Metabolic Disorders and Stroke Part 1: Fabry Disease and Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Strokelike Episodes [Neurological Review]
Evolution and disease converge in the mitochondrion.
Basic mechanisms of neurodegeneration: a critical update.
Mitochondrial Medicine for Neurodegenerative Diseases.
Mitochondrial DNA (mtDNA) Biogenesis: Visualization and Duel Incorporation of BrdU and EdU Into Newly Synthesized mtDNA In Vitro

Recent Mitochondria News

Boy's rare disease inspires support group - CBC.ca
Musk ox population decline due to climate, not to humans, study finds - Eureka! Science News
Speed Reading of DNA May Help Cancer Treatment - New York Times
I'm a starry-eyed techno-utopian, and proud of it - ScienceBlogs (blog)
Research Casts Doubt on Forensic DNA Technique - Wired News
SCIENCE: Aging-related protein's function unraveled in fruit flies - North County Times
RE: Discussing Book of Mormon anachronisms - OmniNerd (blog)
Nephrology: New Gene Linked to Kidney Disease - Science Daily (press release)
Mitochondria (the Powerhouses of our Cells) and Brain Disease - Student Pulse

Recent Mitochondria Publications compiled by Ion Channel Media Group

NJ Robinson et al. Copper Metallochaperones. Annu Rev Biochem
MD Hirschey et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature
Q Zhang et al. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature
Y He et al. Heteroplasmic mitochondrial DNA mutations in normal and tumour cells. Nature
D Di Bella et al. Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28. Nat Genet
KJ Craft et al. Population genetics of ecological communities with DNA barcodes: An example from New Guinea Lepidoptera. Proc Natl Acad Sci U S A
L Bonapace et al. Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance. J Clin Invest
GA Borillo et al. Pim-1 Kinase Protects Mitochondrial Integrity in Cardiomyocytes. Circ Res
C Vives-Bauza et al. PINK1/Parkin direct mitochondria to autophagy. Autophagy

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